Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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811
Tocris Bioscience™ CATPB
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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812
Tocris Bioscience™ SAK 3
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Potent CaV3.1/3.3 activator; orally bioavailable
| Target | Cav3.x Channel Activators |
|---|---|
| CAS | 1256269-87-0 |
| Purity | 98% |
| Chemical Name or Material | Ethyl 8′-methyl-2′,4-dioxo-2-(piperidin-1-yl)-2′H-spiro[cyclopent[2]ene-1,3′-imidazo[1,2-a]pyridine]-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H23N3O4 |
813
Tocris Bioscience™ RS 127445 hydrochloride
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CAS: 199864-86-3 Molecular Formula: C17H17ClFN3
| CAS | 199864-86-3 |
|---|---|
| Molecular Formula | C17H17ClFN3 |
814
Tocris Bioscience™ CHS 828
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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NAMPT inhibitor; active in vivo and cytotoxic
| CAS | 200484-11-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H22ClN5O |
| Formula Weight | 371.86 |
815
Tocris Bioscience™ TL 13-110
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for TL 13-112
816
Tocris Bioscience™ SJF 8240
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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c-MET PROTAC™; also degrades exon-14-deleted c-MET
818
Tocris Bioscience™ Nitazoxanide
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Pyruvate flavodoxin/ferredoxin oxidoreductase inhibitor; also inhibits Wnt signaling; broad spectrum anti-infective
819
Tocris Bioscience™ Pomalidomide 4'-PEG5-amine
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
820
Tocris Bioscience™ ARV 771
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent BET bromodomain PROTAC™; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
821
Tocris Bioscience™ SJFa SJFalpha SJFalpha
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective p38α PROTAC™
822
Tocris Bioscience™ Pomalidomide 5'-piperidine-acid
Cereblon ligand with piperidine linker and terminal acid for onward chemistry
823
Tocris Bioscience™ HEPES
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Multipurpose buffer
824
Tocris Bioscience™ Orlistat
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CAS: 96829-58-2 Molecular Formula: C29H53NO5
| CAS | 96829-58-2 |
|---|---|
| Molecular Formula | C29H53NO5 |
